There's a serial killer on the loose, bent on working his way though the alphabet. There seems little chance of the murderer being caught — until her makes the crucial and vain mistake of challenging Hercule Poirot to frustrate his plans ...

When Chubb University biochemist Millie Hunter notices that a deadly neurotoxin is missing from her laboratory refrigerator, she immediately goes to her father, who is also CT's Chief Medical Examiner. They both know that the situation is grave; the poison shuts down the nervous system and is virtually impossible to stop. Soon, as bodies pile up and the coroner keeps pointing to the neurotoxin, Captain Carmine Delmonico must find the killer fast.